Ozone therapy can be used in a number of ways to preserve and restore health in the body. It can be used medically and cosmetically to accomplish this and is applied with the following methods:
- Directly to the tissue. If you undergo ozone therapy for an extremity problem or wound, the ozone gas will likely be directly applied to the affected part of the body. The gas is administered in a protective covering.
- Intravenously. To treat internal disorders, such as HIV, the ozone gas is usually dissolved into blood that was taken from you. The gas dissolved in your blood is then injected back into you through an IV. Intravenous use does carry the risk of causing an embolism through the formation of air bubbles.
- Intramuscularly. Ozone therapy is also available as an intramuscular injection. For this injection, the ozone gas is often mixed with oxygen before administration.
Some of these are demonstrated in the following ozone therapy treatments:
Cosmetic
Ozone therapy is a remedy for rejuvenation of skin, restoring the barrier, immune, water-retaining, reparative and separative functions of skin as well as improving its structure.
Especially noticeable and fast results through ozone therapy are observed in patients with a diagnosis of “skin stress”.
The treatments involve intra dermal injections of ozone, but can also include a series of ozone saunas as well as the application of ozonated oils.

Limb Bagging Therapy
This treatment involves isolating the area that is receiving treatment with a plastic bag for external ozone application. A mixture of oxygen and ozone is then infused and extracted after a period of time. The ozone disinfects, activates blood circulation and speeds up the healing of the wound.
Hyperbaric MAHT
Hyperbaric MAHT is a form of Autohemotherapy, with ozone volume being infused into the blood under mild hyperbaric pressure. This mild hyperbaric pressure results in a greater rate of infusion of ozone into the whole blood volume, which in turn results in increased effectiveness of the treatment protocol.
The most important indications for Hyperbaric MAHT treatments are: arterial circulatory disorders, systemic infections, and diseases occurring in the context of immune deficiencies, e.g. rheumatism/arthritis, lupus, systemic candida, etc.
Major Autohemotherapy (MAHT)
MAHT is the most important form of low-risk systemic ozone application. The ozone and blood reaction takes place outside of the patient’s body, after which his or her own blood is re-infused with its activated red blood cells and activated immunocompetent cells.
A dose of 50-150 ml of the patient’s blood is withdrawn, and enriched with an exactly dosed quantity of ozone outside of the body. The ozone is then passed through the blood in the form of extremely fine bubbles and the freshly ozonated blood is then administered back to the patient via normal infusion.
The most important indications for MAHT (Major Autohemotherapy) treatments are: arterial circulatory disorders, systemic infections, and diseases occurring in the context of immune deficiencies, e.g. rheumatism/arthritis, lupus, systemic candida, etc.
Minor Autohemotherapy
This is a brief procedure where 5-10 ml of blood is taken from a patient’s vein and then enriched in a 20 ml syringe containing 10 ml of ozone. The ozone enriched blood is then injected into the patient’s gluteal muscle or under the patient’s skin.
The immune system reacts to this ozone enriched blood with higher activity and production of antibodies.

Prolozone
Prolozone is a technique that marries concepts from neural therapy, Prolotherapy, and ozone therapy.
This involves injecting various combinations of procaine, anti-inflammatory medications/homeopathics, vitamins, minerals, proliferatives, and a mixture of ozone/oxygen gas into degenerated or injured joints, and into areas of pain.
The result of this combination is remarkable in that damaged tissues can be regenerated, and otherwise untreatable pain can be permanently cured.
Conditions responsive to Prolozone
• Carpal tunnel syndrome
• Chronic back pain
• Chronic neck pain
• Degenerated discs
• Degenerative & arthritic ankles
• Degenerative & arthritic hips
• Degenerative & arthritic knees
• Dental infections
• Heel spurs
• Neuromas
• Non-union fractures
• Painful scars
• Pelvic disorders
• Plantar fasciitis
• Post-op pain
• Rotator cuff injuries
• Sciatica
• Sinus infections
• Sports injuries
• Tennis elbow
• TMJ.
This may seem like a new treatment, but it is acknowledged that Medical Ozone has been used to disinfect medical supplies and treat different conditions for more than 100 years.
So, is ozone therapy positioned to become the next medical breakthrough?
While medical practitioners have not been completely won over yet (and neither have organizations like the FDA), experimental evidence points to the potential benefits, especially as a supplementary treatment alongside conventional medicine. It is safe and can be used as a standalone therapy.
Source: Medicalozone, Healthline